Matrix Metalloproteinase-2 (MMP-2) ELISA
The K-ASSAY®Human Matrix Metalloproteinase-2 (MMP-2) ELISA is an enzyme-linked immunosorbent assay for the quantitative determination of MMP-2 in human cell culture supernatant, serum and plasma.
MMP-2, also known as gelatinase A, is a 72- kDa enzyme involved in cleaving components of the extraceullar matrix and signal transduction molecules. MMPs are as latent pro-enzymes that are activated by proteolytic cleavage. MMP-2 can be activated extracellularly by proteases or intracellularly by S-glutathiolation. It plays an essential role in angiogenesis and arteriogenesis.
MMP-2 expression is increased in tissue ischemia associated with some cancers as well as cardiovascular and kidney diseases.
Cell culture supernatant, serum, plasma
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MMP-2 ELISA - Product Insert | "Research Use Only"
Diabetic Nephropathy - BioMarker Overview
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