Tissue Inhibitor of Metalloproteinase-1 (TIMP-1) ELISA

BioMarkers | Diabetic Nephropathy | Fibrosis


The K-ASSAY®Human Tissue Inhibitor of Metalloproteinase-1 (TIMP-1) ELISA is an enzyme-linked immunosorbent assay for the quantitative determination of TIMP1 in human cell culture supernatant, serum, plasma and saliva.

TIMP-1, also known as erythroid-potentiating activity (EPA), is a 22- kDa glycoprotein that regulates connective tissue turnover by inhibiting the activity of matrix metalloproteinases (MMPs) such as MMP-2 and disintegrin-metalloproteinases. It also plays a role in cell differentiation, migration and apoptosis.

Imbalance of TIMPs is associated with tissue remodeling in atherosclerosis, fibrosis and inflammatory bowel disease (IBD) as well as degenerative diseases such as rheumatoid arthritis.



Species reactivity


Sample type

Cell culture supernatant, serum, plasma, urine

Assay type

Sandwich (quantitative)


15.6–1,000 pg/mL

Detection method


Assay time

3h 30min


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Check also our broad collection of ANIMAL TIMP-1 ELISA Kits


Partner: Kamiya BioMedical Company

TIMP-1 ELISA - Product Insert | "Research Use Only"

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Download the BioMarker Overview Table here, including detailed information about 28 suggested biomarker assays.

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