Monocyte Chemotactic Protein-1 (MCP-1) ELISA

BioMarkers | Diabetic Nephropathy | Inflammation


The K-ASSAY®Human Monocyte Chemoattractant Protein-1 (MCP-1) ELISA is an enzyme-linked immunosorbent assay for the quantitative determination of MCP-1 in human cell culture supernatant, serum, plasma and amniotic fluid.

MCP-1, also known as CCL2 and monocyte chemotactic and activating factor (MCAF), is one of the most thoroughly studied CC chemokines. It plays a central role in the recruitment of monocytes, T lymphocytes and NK cells to sites of injury/inflammation. In the vasculature, MCP-1 released by endothelial and smooth muscle cells binds to its complementary receptor (CCR2) on monocytes leading to their infiltration and activation in the subluminal space.

Elevated levels of MCP-1 is seen in diseases with a strong inflammatory component, such as atherosclerosis, nephropathy, rheumatoid arthritis, multiple sclerosis, and nonalcoholic steatohepatitis (NASH).



Species reactivity


Sample type

Cell culture supernatant, serum, plasma, amniotic fluid

Assay type

Sandwich (quantitative)


74–760 pg/mL

Detection method


Assay time

2h 30min


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Check also our collection of ANIMAL MCP-1 ELISA Kits


Partner: Kamiya BioMedical Company

MCP-1 ELISA - Product Insert | "Research Use Only"

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