Tumor Necrosis Factor Alpha (TNFα) ELISA
BioMarkers | Diabetic Nephropathy | Inflammation
Description
The K-ASSAY®Human Tumor Necrosis Factor alpha (TNFα) ELISA is an enzyme-linked immunosorbent assay for the quantitative determination of TNFα in human cell culture supernatant, serum and plasma.
TNFα is a central regulator of inflammation and represents one of the cytokines of the acute phase response in the liver. It is produced by a variety of cell types, such as macrophages, lymphocytes and endothelial cells. Large amounts of TNF are released following exposure to bacterial products (for example lipopolysaccharide) as well as interleukins (IL)-1 and -6.
Upregulation of TNFα is observed in several inflammatory diseases including: inflammatory bowel disease (IBD), psoriasis, rheumatoid arthritis, diabetic nephropathy and cardiovascular diseases. Purified TNFα has shown cytotoxic and cytostatic activities against various human tumor cell lines.
Specifications
Species reactivity | Human |
Sample type | Cell culture supernatant, serum, plasma |
Assay type | Sandwich (quantitative) |
Range | 15.6–1,000 pg/mL |
Detection method | Colormetric |
Assay time | 3h 30min |
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Check also our collection of ANIMAL TNFα ELISA Kits
Partner: Kamiya BioMedical Company
TNFα ELISA - Product Insert | "Research Use Only"
Diabetic Nephropathy - BioMarker Overview
Download the BioMarker Overview Table here, including detailed information about 28 suggested biomarker assays.
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