Alpha 1-Microglobulin ELISA

BioMarkers | Diabetic Nephropathy | Injury and Dysfunction

Description

The K-ASSAY┬« Human alpha1-Microglobulin (A1M) ELISA is designed for the quantitative determination of A1M in serum, plasma, cell culture supernatants, body fluid and tissue homogenate.

A1M is a low-molecular-weight protein of 26 kDa part of the lipocalin protein superfamily. It is synthesized in the liver, freely filtered by glomeruli and reabsorbed in the renal proximal tubule. It has immunomodulatory functions including inhibition of T lymphocytes stimulation and neutrophil chemotaxis.

Increased urinary concentration of A1M indicates proximal tubule injury and/or impaired proximal tubular function. It useful for diagnosing kidney disorders such as diabetic nephropathy.

 

Specifications

Species reactivity

Human

Sample type

Serum, plasma, cell culture supernatants, body fluid and tissue homogenate.

Assay type

Competitive (quantitative)

Sensitivity

0.1 mg/L

Detection method

Colormetric

Assay time

1h 30min

 

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Check also our collection of ANIMAL A1M ELISA Kits

 

Partner: Kamiya BioMedical Company

A1M ELISA - Product Insert | "Research Use Only"

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Download the BioMarker Overview Table here, including detailed information about 28 suggested biomarker assays.

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