Alpha 1-Microglobulin ELISA
BioMarkers | Diabetic Nephropathy | Injury and Dysfunction
Description
The K-ASSAY® Human alpha1-Microglobulin (A1M) ELISA is designed for the quantitative determination of A1M in serum, plasma, cell culture supernatants, body fluid and tissue homogenate.
A1M is a low-molecular-weight protein of 26 kDa part of the lipocalin protein superfamily. It is synthesized in the liver, freely filtered by glomeruli and reabsorbed in the renal proximal tubule. It has immunomodulatory functions including inhibition of T lymphocytes stimulation and neutrophil chemotaxis.
Increased urinary concentration of A1M indicates proximal tubule injury and/or impaired proximal tubular function. It useful for diagnosing kidney disorders such as diabetic nephropathy.
Specifications
Species reactivity | Human |
Sample type | Serum, plasma, cell culture supernatants, body fluid and tissue homogenate. |
Assay type | Competitive (quantitative) |
Sensitivity | 0.1 mg/L |
Detection method | Colormetric |
Assay time | 1h 30min |
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Check also our collection of ANIMAL A1M ELISA Kits
Partner: Kamiya BioMedical Company
A1M ELISA - Product Insert | "Research Use Only"
Diabetic Nephropathy - BioMarker Overview
Download the BioMarker Overview Table here, including detailed information about 28 suggested biomarker assays.
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