Cystatin C ELISA
BioMarkers | Diabetic Nephropathy | Injury and Dysfunction
Description
The K-ASSAY®Human Cystatin C ELISA is an enzyme immunoassay for the quantitative determination of human cystatin C in fluids and cell culture supernatants.
Cystatin C is a low molecular weight (approximately 13.3 kDa) plasma protein produced by all nucleated human cells that belongs to the type 2 cystatin protease inhibitor family. The kidney is the major site (>99%) of cystatin C clearance, predomantly via glomerular filtration and catabolism in the proximal tubule.
Serum Cystatin C has been proposed as an alternative marker of renal dysfunction to serum creatinine in patients with renal impairment, including diabetic nephropathy and chronic kidney disease. Serum Cystatin C levels rise in proportion to decreased glomerular filtration rate (GFR).
Specifications
Species reactivity | Human |
Sample type | Serum, plasma, saliva, urine, milk, and human cell culture supernatant |
Assay type | Sandwich (quantitative) |
Range | 312pg/mL – 20,000pg/mL |
Detection method | Colormetric |
Assay time | 4hrs |
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Check also our broad collection of ANIMAL Cystatin C ELISA Kits
Partner: Kamiya BioMedical Company
Cystatin C ELISA - Product Insert | "Research Use Only"
Diabetic Nephropathy - BioMarker Overview
Download the BioMarker Overview Table here, including detailed information about 28 suggested biomarker assays.
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