Liver-type Fatty Acid Binding Protein (L-FABP) ELISA
The K-ASSAY® Human Liver Fatty Acid Binding Protein (FABP)-1 ELISA is designed for the quantitative determination of human FABP1 in serum, plasma, cell culture supernatant, body fluid and tissue homogenate.
FABP1 is highly expressed in the liver as well as in the intestine, kidney and lung. It plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes and fatty acid trafficking in order to prevent lipotoxicity of free fatty acids. FABP1 has a unique structure compared to other members of the FABP family, allowing it to bind multiple ligands simultaneously.
Dysregulation of FABP1 is linked to metabolic conditions such as obesity and nonalcoholic fatty liver disease (NAFLD). High urinary L-FABP is correlated with the development of end-stage renal disease and cardiovascular disease.
Serum, plasma, cell culture supernatant, body fluid and tissue homogenate
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L-FABP ELISA - Product Insert | "Research Use Only"
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