Liver-type Fatty Acid Binding Protein (L-FABP) ELISA
BioMarkers | Diabetic Nephropathy | Injury and Dysfunction
Description
The K-ASSAY® Human Liver Fatty Acid Binding Protein (FABP)-1 ELISA is designed for the quantitative determination of human FABP1 in serum, plasma, cell culture supernatant, body fluid and tissue homogenate.
FABP1 is highly expressed in the liver as well as in the intestine, kidney and lung. It plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes and fatty acid trafficking in order to prevent lipotoxicity of free fatty acids. FABP1 has a unique structure compared to other members of the FABP family, allowing it to bind multiple ligands simultaneously.
Dysregulation of FABP1 is linked to metabolic conditions such as obesity and nonalcoholic fatty liver disease (NAFLD). High urinary L-FABP is correlated with the development of end-stage renal disease and cardiovascular disease.
Specifications
Species reactivity | Human |
Sample type | Serum, plasma, cell culture supernatant, body fluid and tissue homogenate |
Assay type | Competitive |
Sensitivity | 1.0 ng/mL |
Detection method | Colormetric |
Assay time | 1h 30min |
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Check also our collection of ANIMAL L-FABP ELISA Kits
Partner: Kamiya BioMedical Company
L-FABP ELISA - Product Insert | "Research Use Only"
Diabetic Nephropathy - BioMarker Overview
Download the BioMarker Overview Table here, including detailed information about 28 suggested biomarker assays.
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