Liver-type Fatty Acid Binding Protein (L-FABP) ELISA

BioMarkers | Diabetic Nephropathy | Injury and Dysfunction

Description
The K-ASSAY┬« Human Liver Fatty Acid Binding Protein (FABP)-1 ELISA is designed for the quantitative determination of human FABP1 in serum, plasma, cell culture supernatant, body fluid and tissue homogenate.

FABP1 is highly expressed in the liver as well as in the intestine, kidney and lung. It plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes and fatty acid trafficking in order to prevent lipotoxicity of free fatty acids. FABP1 has a unique structure compared to other members of the FABP family, allowing it to bind multiple ligands simultaneously.

Dysregulation of FABP1 is linked to metabolic conditions such as obesity and nonalcoholic fatty liver disease (NAFLD). High urinary L-FABP is correlated with the development of end-stage renal disease and cardiovascular disease.

 

Specifications

Species reactivity

Human

Sample type

Serum, plasma, cell culture supernatant, body fluid and tissue homogenate

Assay type

Competitive

Sensitivity

1.0 ng/mL

Detection method

Colormetric

Assay time

1h 30min

 

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Check also our collection of ANIMAL L-FABP ELISA Kits

 

Partner: Kamiya BioMedical Company

L-FABP ELISA - Product Insert | "Research Use Only"

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