N-Acetyl-beta-Glucosaminidase (NAG) ELISA
The K-ASSAY®Human N-acetyl-β D glucosaminidase (NAG) is a quantitative assay of human NAG in serum, plasma, cell culture supernatant body fluid and tissue homogenate.
NAG is a high molecular weight (140 kDa) lysosomal enzyme. It shows high activity in renal proximal tubule cells. Following tubular injury, NAG leaks into the tubular fluid and is detected in the urine. In some studies, urinary NAG : Creatinine is used as a surrogate marker of renal function.
Abnormally high levels of NAG are detected in kidney diseases including diabetic nephropathy, glomerulonephritis, tubulointerstitial diseases, renal allograft rejection, and toxic renal injury.
Serum, plasma, cell culture supernatant body fluid and tissue homogenate
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NAG ELISA - Product Insert | "Research Use Only"
Diabetic Nephropathy - BioMarker Overview
Download the BioMarker Overview Table here, including detailed information about 28 suggested biomarker assays.
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