Podocalyxin (PCX) ELISA
The K-ASSAY® Human Podocalyxin (PCX) ELISA is a quantitative assay of human PCX in serum, plasma, cell culture supernatant body fluid and tissue homogenate.
PCX is a member of the CD34 family of transmembrane sialomucins expressed by kidney podocytes, hematopoietic progenitors, vascular endothelia, and a subset of neurons. It is a major constituent of the glycocalyx of podocytes in the glomerulus, where it plays a role in maintaining podocyte morphology.
Dysregulated expression of PCX has been implicated in cancer malignancy. Increased urinary PCX levels are seen in patients with diabetes, nephropathy and lupus nephritis.
Serum, plasma, cell culture supernatant body fluid and tissue homogenate
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PCX ELISA - Product Insert | "Research Use Only"
Diabetic Nephropathy - BioMarker Overview
Download the BioMarker Overview Table here, including detailed information about 28 suggested biomarker assays.
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