8-hydroxy-2’-deoxyguanosine (8-OHdG) ELISA
BioMarkers | Diabetic Nephropathy | Oxidative Stress
Description
The K-ASSAY®8-hydroxy-2’-deoxyguanosine (8-OHdG) is a quantitative assay of 8-OHdG in urine, serum, tissue and other biological samples.
8-OHdG is a specific marker of DNA oxidative damage produced by oxidation of deoxyguanosine by reactive oxygen and nitrogen species..
Elevated levels of 8-OHdG serve as a biomarker of oxidative stress, which is associated with various acute and chronic humans diseases. Increased plasma or urinary 8-OHdG is reported in chronic liver diseases, diabetes-associated complications (nephropathy, retinopathy), cardiovascular disease and various cancers.
Specifications
Species reactivity | Human |
Sample type | Urine, serum, tissue, biological samples |
Assay type | Competitive (quantitative) |
Range | 0.125–10 ng/mL |
Detection method | Colormetric |
Assay time | Overnight incubation |
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Check also our broad collection of ANIMAL 8-OHdG ELISA Kits
Partner: Kamiya BioMedical Company
8-OHdG - Product Insert | "Research Use Only"
Diabetic Nephropathy - BioMarker Overview
Download the BioMarker Overview Table here, including detailed information about 28 suggested biomarker assays.
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